Epigenetic Therapy Shows Promise
Promising Data in SU2C
Blood Test for Cancer Gets a Boost
Meet the SU2C Dream Teams
A New Script For Cancer Research
The SU2C-MRA Melanoma Dream Team will investigate the utility of personalized target/therapy identification in patients with BRAFwt metastatic melanoma – a subtype of melanoma for which there are currently few treatment options. The team hopes that an individualized medicine approach to the treatment of BRAFwt metastatic melanoma will not only lead to therapeutic benefit for this patient population, but may also be beneficial to many other tumor and disease types.
"Melanoma has been a success story in the past year, but that success affects about half of the patients, at best. We just said, we’ve got to go after that group that just desperately needs our help."
- Dr. Jeffrey M. Trent, Ph.D., F.A.C.M.G.
The PI3K Dream Team is developing clinical techniques that may lead to therapeutic combinations able to hit multiple targets in the complex pathways that contribute to cancer cell growth in a variety of women’s cancers, such as breast, ovarian, and endometrial.
The Pancreatic Dream Team is attacking the lethal problem of pancreatic cancer with a dual approach: exploring advanced imaging techniques to determine what nutrients pancreatic cancers require to grow and survive; using the results of these tests to design individualized treatment combinations that will cut off the fuel supply to pancreatic tumors with the hope of increasing survival and quality of life for pancreatic cancer patients.
“Every single person on this team has lost somebody to pancreatic cancer… many of us see patients with it every single day… We can do things, we can help with their pain, we can improve their survival some. But we want to do something dramatic.”
- Dr. Daniel D. Von Hoff, M.D
The CTC Dream Team is using a novel and radically different approach to detecting
and isolating Circulating Tumor Cells (CTCs), pursuing revolutionary diagnostic and treatment strategy tools. The fundamental technology involved takes advantage of microscopic fluid dynamics to construct a chip with 100 times greater sensitivity than existing technology.
The Epigenetics Dream Team is delivering on the promise of epigenetic therapy in clinical practice. The team is developing biomarkers that can predict and monitor the efficacy of epigenetic therapies, and conducting clinical trials that will bring epigenetic therapy to the forefront of cancer management
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The Breast Cancer Dream Team has created a fully integrated translational research approach which is rapidly moving toward more effective, less toxic therapies for the three major breast cancer subtypes.
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